130-89-2 Quinine HCl AKSci I951
 
 
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  I951    
Quinine HCl
, 98%
 



IDENTITY
CAS Number:130-89-2
MDL Number:MFCD00078498
MF:C20H24N2O2.HCl
MW:360.88
EINECS:205-003-2
BRN:91867
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98%
Spectra:NMR, LCMS
Physical Form:White to off-white powder
Melting Point:150-160°C
Long-Term Storage:Store long-term in a cool, dry place
HAZARDOUS MATERIALS INFORMATION
Not hazardous material

BIOLOGICAL INFO
Form:HCl salt

REVIEW

 The theorized mechanism of action for quinine and related anti-malarial drugs is that these drugs are toxic to the malaria parasite. Specifically, the drugs interfere with the parasite's ability to break down and digest hemoglobin. Consequently, the parasite starves and/or builds up toxic levels of partially degraded hemoglobin in itself.

REFERENCES
[1]Paintaud G, Alvan G, Berninger E, Gustafsson LL, Idrizbegovic E, Karlsson KK, Wakelkamp M: The concentration-effect relationship of quinine-induced hearing impairment. Clin Pharmacol Ther. 1994 Mar;55(3):317-23.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


RELATED PRODUCTS
X7113Quinine
I951Quinine HCl
M874Quinine sulfate dihydrate
B338Quinidine
B337Dihydroquinine
S101Dihydroquinidine

Current as of July 23, 2021


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CATEGORIES

 APIs and Bioactives > Antimalarials
 Chiral Synthesis >
 Chiral Synthesis >


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