[56-54-2] Quinidine AKSci B338
 
 
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  B338    
Quinidine
 
Conquinine




IDENTITY
CAS Number:[56-54-2]
MDL Number:MFCD00135581
MF:C20H24N2O2
MW:324.42
SPECIFICATIONS & PROPERTIES
Available Spectra:NMR, LCMS, FT-IR, HPLC, Polarimetry
Physical Form:White powder
Melting Point:171-173°C
Optical Rotation:+260° (c=1 in Ethanol)
Long-Term Storage:Store long-term at 2-8°C
UN #:UN2811
Hazard Class:6.1
Packing Group:III
Note:~20% Dihydroquinidine

BIOLOGICAL INFO
Application(s):class I antiarrhythmic agent

REVIEW

 Quinidine acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. The antiarrhythmic actions are mediated through effects on sodium channels in Purkinje fibers. Quinidine may also act on the slow inward calcium current (ICa), the rapid (IKr) and slow (IKs) components of the delayed potassium rectifier current, the inward potassium rectifier current (IKI), the ATP-sensitive potassium channel (IKATP) and Ito.

GHS

Pictograms

Signal Word
Danger

Hazard Statements
H301

Precautionary Statements
P264; P270; P301+P310; P321; P330; P405; P501


RELATED PRODUCTS
X7113Quinine
I951Quinine HCl
M874Quinine sulfate dihydrate
B338Quinidine
B337Dihydroquinine
S101Dihydroquinidine

Current as of March 27, 2017


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CATEGORIES

 APIs and Bioactives > Arrhythmia, Alkaloids


PubChem