66722-44-9 Bisoprolol AKSci K094
 
 
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  K094    AKSci Reference Standard
Bisoprolol
, 98% (GC)
 
1-{4-{[2-(1-Methylethoxy)ethoxy]methyl}phenoxy}-3-[(1-methylethyl)amino]-2-propanol




IDENTITY
CAS Number:66722-44-9
MDL Number:MFCD00865795
MF:C18H31NO4
MW:325.44
SPECIFICATIONS & PROPERTIES
Purity:98% (GC)
Spectra:LCMS, GC
Physical Form:Colorless to white to off-white liquid, paste
Long-Term Storage:Store long-term at 2-8°C

BIOLOGICAL INFO
Application(s):beta-1-Adrenergic receptor blocker
Form:Free base

REVIEW

 Bisoprolol selectively blocks catecholamine stimulation of β1-adrenergic receptors in the heart and vascular smooth muscle. This results in a reduction of heart rate, cardiac output, systolic and diastolic blood pressure, and possibly reflex orthostatic hypotension. At higher doses (e.g. 20 mg and greater) bisoprolol may competitively block ?2-adrenergic receptors in bronchial and vascular smooth muscle causing bronchospasm and vasodilation.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H302

Precautionary Statements
P264; P270; P301+P312; P330; P501


RELATED PRODUCTS
G646Bisoprolol hemifumarate
K094Bisoprolol

Current as of March 20, 2019

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Beta Blockers


PubChem