REVIEW Helpful in delineating the critical role of the MLK (mixed-lineage kinases) kinases in the JNK pathway and in neuroprotection in various cell types and neuronal populations.
REFERENCES
[1]
R. Hudkins, J. Diebold, M. Tao. et al. Mixed-Lineage Kinase 1 and Mixed-Lineage Kinase 3 Subtype-Selective Dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: Optimization, Mixed-Lineage Kinase 1 Crystallography, and Oral in Vivo Activity in 1-Methyl-4-phenyltetrahydropyridine Models. Journal of Medicinal Chemistry 2008 51 (18), 5680-5689
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