70775-75-6 Octenidine dihydrochloride AKSci X4026
 
 
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  X4026    
Octenidine dihydrochloride
, 98%
 
N,N'-[Decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene]bis(octylammonium) dichloride




IDENTITY
CAS Number:70775-75-6
MDL Number:MFCD01938808
MF:C36H64Cl2N4
MW:623.83
EINECS:274-861-8
SPECIFICATIONS & PROPERTIES
Purity:98%
Physical Form:White to light yellow to yellow crystal or powder
Melting Point:208-217°C
Long-Term Storage:Store at room temperature
UN #:Not hazmat

REVIEW

 Octenidine dihydrochloride is a cationic surfactant and bis-(dihydropyridinyl)-decane derivative used in concentrations of 0.1-2.0% for skin, mucous membrane and wound antisepsis. It is similar in its action to quaternary ammonium compounds, but is of somewhat broader spectrum of activity. Octenidine is currently increasingly used in continental Europe as a substitute for quats or chlorhexidine in water- or alcohol-based skin, mucosa and wound antiseptics. In aqueous formulations, it is often potentiated with addition of 2-phenoxyethanol.

REFERENCES
[1]Bailey, Denis M.; DeGrazia, C. George; Hoff, Stephanie J.; Schulenberg, Patsy L.; O'Connor, John R.; Paris, Donald A.; Slee, Andrew McKenzie Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque Journal of Medicinal Chemistry (1984), 27(11), 1457-64.
[2] Beilfuss, Wolfgang; Gradtke, Ralf; Streek, Michael Process for the preparation of bis(4-amino-1-pyridinium)alkane salts Eur. Pat. Appl. (2001), EP 1123927 A1 20010816.
[3] Krishna BV, Gibb AP. Use of octenidine dihydrochloride in meticillin-resistant Staphylococcus aureus decolonisation regimens: a literature review. J Hosp Infect. 2010 Mar;74(3):199-203.
[4] Hübner NO, Siebert J, Kramer A.Octenidine dihydrochloride, a modern antiseptic for skin, mucous membranes and wounds.Skin Pharmacol Physiol. 2010;23(5):244-58.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


RELATED PRODUCTS
K205Octenidine
X4026Octenidine dihydrochloride

Current as of December 12, 2018


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CATEGORIES

 APIs and Bioactives > Antiseptics
 Specialty Chemicals > Surfactants


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