58543-16-1 Rebaudioside-A AKSci X1217
 
 
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  X1217    
Rebaudioside-A
, 98% (HPLC)
 



IDENTITY
CAS Number:58543-16-1
MDL Number:MFCD02183463
MF:C44H70O23
MW:967.014
BRN:6470556
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):White to off-white powder or solid
Melting Point:242-244°C
Optical Rotation:-33.0±3.0°, (c=1% in H2O)
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW

 Rebaudioside-A is a steviol glycoside responsible for the sweet taste of the leaves of the stevia plant. These compounds range in sweetness from 300 times sweeter than sucrose. Rebaudioside-A is heat-stable, pH-stable, does not ferment, and does not induce a glycemic response when ingested, thus making them attractive as natural sweeteners to diabetics and others on carbohydrate-controlled diets. It has recently been shown potently stimulates the insulin secretion, and this insulinotropic effect of rebaudioside-A has been shown to be mediated via inhibition of ATP-sensitive K(+)-channels and requires the presence of high glucose.

REFERENCES
[1]Kaneda, Norito; Kasai, Ryoji; Yamasaki, Kazuo; Tanaka, Osamu. Chemical studies on sweet diterpene-glycosides of Stevia rebaudiana: conversion of stevioside into Rebaudioside A. Chemical & Pharmaceutical Bulletin. (1977) 25(9): 2466-7.
[2] Kim, Darrick S. H. L. Synthetic investigations on steviol, stevioside, and rebaudioside A, and their applications as starting materials. Medicinal and Aromatic Plants--Industrial Profiles. (2002) 19(Stevia): 119-137.
[3] Abudula R, Matchkov VV, Jeppesen PB, Nilsson H, Aalkjaer C, Hermansen K. Rebaudioside A directly stimulates insulin secretion from pancreatic beta cells: a glucose-dependent action via inhibition of ATP-sensitive K-channels. Diabetes Obes Metab. (2008) Nov;10(11): 1074-85.
[4] Kuroda, Akio; Kamiyama, Sadao Stevia leaf extract purification Jpn. Kokai Tokkyo Koho (1979), JP 54076600 A 19790619

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


RELATED PRODUCTS
X1217Rebaudioside-A
S623Stevioside, tech.

Current as of January 26, 2022


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CATEGORIES

 APIs and Bioactives >
 Specialty Chemicals > Sugar Substitutes
 Specialty Chemicals > Sugar Substitutes


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