150322-43-3 Prasugrel AKSci W0064
 
 
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  W0064    AKSci Reference Standard
Prasugrel, 98% (HPLC)
 
Effient
Efient
Prasita
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IDENTITY
CAS Number:150322-43-3
MDL Number:MFCD09954140
MF:C20H20FNO3S
MW:373.44
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:122-127°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 30mg/mL; H2O: <1mg/mL; EtOH: 7mg/mL
Application(s):Purinergic P2Y Receptor Antagonist
Form:Free Base

REVIEW
 Prasugrel is platelet inhibitor for the reduction of thrombotic cardiovascular events. Prasugrel is a member of the thienopyridine class of ADP receptor inhibitors. The drug reduces the aggregation (clumping) of platelets by irreversibly binding to P2Y12 receptors.

REFERENCES
[1]Gurbel PA, Erlinge D, Ohman EM, Neely B, Neely M, Goodman SG, Huber K, Chan MY, Cornel JH, Brown E, Zhou C, Jakubowski JA, White HD, Fox KA, Prabhakaran D, Armstrong PW, Tantry US, Roe MT; TRILOGY ACS Platelet Function Substudy Investigators (2012). Platelet function during extended prasugrel and clopidogrel therapy for patients with ACS treated without revascularization: the TRILOGY ACS platelet function substudy. JAMA. 308(17):1785-94. PMID 23117779.
[2] Diletti R, Serruys PW, Farooq V, Sudhir K, Dorange C, Miquel-Hebert K, Veldhof S, Rapoza R, Onuma Y, Garcia-Garcia HM, Chevalier B (2012). ABSORB II randomized controlled trial: a clinical evaluation to compare the safety, efficacy, and performance of the Absorb everolimus-eluting bioresorbable vascular scaffold system against the XIENCE everolimus-eluting coronary stent system in the treatment of subjects with ischemic heart disease caused by de novo native coronary artery lesions: rationale and study design. Am Heart J. 164(5):654-63. PMID 23137495.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

RELATED PRODUCTS
W0064Prasugrel

Current as of December 26, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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