107133-36-8 Perindopril erbumine AKSci V2111

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V2111
Perindopril erbumine, 98%

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Perindopril

Perindopril tert-butylamine

IDENTITY
CAS Number:	107133-36-8
MDL Number:	MFCD02313824
MF:	C23H43N3O5
MW:	441.60

SPECIFICATIONS & PROPERTIES
Purity:	98%
Physical Form:	White powder
Melting Point:	126-130°C
Long-Term Storage:	Store long-term at 2-8°C
UN #:	Not hazmat

BIOLOGICAL INFO
Solubility:	DMSO: >10 mg/mL, H2O: 10mg/mL
Application(s):	Non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor; Antihypertensive Agent
Form:	t-Butylamine

REVIEW
Perindopril is a long-acting ACE inhibitor that is used to treat high blood pressure, heart failure or stable coronary artery disease.

REFERENCES

[1]	Hurst M, Jarvis B: Perindopril: an updated review of its use in hypertension. Drugs. 2001;61(6):867-96.
[2]	Jastrzebskal M, Widecka K, Naruszewicz M, Ciechanowicz A, Janczak-Bazan A, Foltynska A, Goracy I, Chetstowski K, Wesotowska T: Effects of perindopril treatment on hemostatic function in patients with essential hypertension in relation to angiotensin converting enzyme (ACE) and plasminogen activator inhibitor-1 (PAI-1) gene polymorphisms. Nutr Metab Cardiovasc Dis. 2004 Oct;14(5):259-69.
[3]	Parker E, Aarons L, Rowland M, Resplandy G: The pharmacokinetics of perindoprilat in normal volunteers and patients: influence of age and disease state. Eur J Pharm Sci. 2005 Sep;26(1):104-13.
[4]	Simpson D, Noble S, Goa KL: Perindopril: in congestive heart failure. Drugs. 2002;62(9):1367-77; discussion 1378-9.