[865-21-4] Vinblastine AKSci Q943
 
 
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  Q943    
Vinblastine
, 94%
 



IDENTITY
CAS Number:[865-21-4]
MDL Number:MFCD05662370
MF:C46H58N4O9
MW:810.97
SPECIFICATIONS & PROPERTIES
Purity:94%
Available Spectra:LCMS, HPLC
Physical Form:White to light yellow powder
Melting Point:211-216°C
Optical Rotation:-32° (c=0.88, MeOH)
Long-Term Storage:Store long-term at 2-8°C

BIOLOGICAL INFO
Application(s):ACHR
Form:Free base

REVIEW

 The antitumor activity of vinblastine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Vinblastine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death.

REFERENCES
[1]Starling D: Two ultrastructurally distinct tubulin paracrystals induced in sea-urchin eggs by vinblastine sulphate. J Cell Sci. 1976 Jan;20(1):79-89.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


RELATED PRODUCTS
F345Vinblastine sulfate
Q943Vinblastine

Current as of September 22, 2017


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CATEGORIES

 APIs and Bioactives > Alkaloids, Chemotherapeutics


PubChem