H2O: >=50 mg/mL, clear, colorless to faintly yellow
REVIEW Menadione sodium bisulfite is a water soluble synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo. It belongs to the Vitamin K class of compounds and these are necessary for the biosynthesis of prothrombin and other blood clotting factors.
Charles, O. W. Review of the isomeric structures and properties of menadione bisulfites. Feedstuffs. (1972) 44(11): 35.
Matveev, K. I.; Odyakov, V. F.; Zhizhina, E. G. New route to vicasol, a water-soluble form of vitamin K3. Russian Journal of Applied Chemistry (Translation of Zhurnal Prikladnoi Khimii). (2001) 74(3): 469-472.
Shmuk, A.; Guseva, A. Synthesis of a water-soluble analog of vitamin K. Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation). (1948) 21: 1180-2.
Carmack, Marvin; Moore, M. B.; Balis, M. Earl The structure of the antihemorrhagic sodium bisulfite addition product of 2-methyl-1,4-naphthoquinone (Menadione), Journal of the American Chemical Society (1950), 72, 844-7.
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