130-37-0 Menadione sodium bisulfite AKSci O420
 
 
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  O420    
Menadione sodium bisulfite
, 98% (HPLC)
 
2-Methyl-1,4-naphthoquinone sodium bisulfite
Vitamin K 3
Dohyfral
more..




IDENTITY
CAS Number:130-37-0
MDL Number:MFCD00051456
MF:C11H9NaO5S
MW:276.24
EINECS:204-987-0
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Physical Form:White to off-white crystalline powder
Melting Point:133-140°C
Long-Term Storage:Store long-term at -20°C

BIOLOGICAL INFO
Solubility:H2O: >=50 mg/mL, clear, colorless to faintly yellow

REVIEW

 Menadione sodium bisulfite is a water soluble synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo. It belongs to the Vitamin K class of compounds and these are necessary for the biosynthesis of prothrombin and other blood clotting factors.

REFERENCES
[1]Charles, O. W. Review of the isomeric structures and properties of menadione bisulfites. Feedstuffs. (1972) 44(11): 35.
[2] Matveev, K. I.; Odyakov, V. F.; Zhizhina, E. G. New route to vicasol, a water-soluble form of vitamin K3. Russian Journal of Applied Chemistry (Translation of Zhurnal Prikladnoi Khimii). (2001) 74(3): 469-472.
[3] Shmuk, A.; Guseva, A. Synthesis of a water-soluble analog of vitamin K. Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation). (1948) 21: 1180-2.
[4] Carmack, Marvin; Moore, M. B.; Balis, M. Earl The structure of the antihemorrhagic sodium bisulfite addition product of 2-methyl-1,4-naphthoquinone (Menadione), Journal of the American Chemical Society (1950), 72, 844-7.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H319

Precautionary Statements
P264; P280; P305+P351+P338; P337+P313


RELATED PRODUCTS
H5002-Methylnaphthoquinone
O420Menadione sodium bisulfite

Current as of July 11, 2020


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CATEGORIES

 APIs and Bioactives > Vitamins


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