HIV protease inhibitor; Azapeptide inhibitor of HIV-1 protease
Form:
Sulfate salt
REVIEW Atazanavir selectively inhibits the virus-specific processing of viral Gag and Gag-Pol polyproteins in HIV-1 infected cells by binding to the active site of HIV-1 protease, thus preventing the formation of mature virions. Atazanavir is not active against HIV-2.
REFERENCES
[1]
Singh, Janak; Pudipeddi, Madhusudhan; Lindrud, Mark D. Bisulfate salt of HIV protease inhibitor.
[2]
Xu, Zhongmin; Singh, Janak; Schwinden, Mark D.; Zheng, Bin; Kissick, Thomas P.; Patel, Bharat; Humora, Michael J.; Quiroz, Fernando; Dong, Lin; Hsieh, Dau-Ming; et al Process Research and Development for an Efficient Synthesis of the HIV Protease Inhibitor BMS-232632 Organic Process Research & Development (2002), 6(3), 323-328.
[3]
Kim, Soojin; Lotz, Bruce T.; Malley, Mary F.; Gougoutas, Jack Z.; Davidovich, Martha; Srivastava, Sushil Synthesis of atazanavir bisulfate and preparation and analysis of novel crystalline forms for administration for treatment of HIV PCT Int. Appl. (2005), WO 2005108349 A2 20051117.
These chemical products are for research and development use only. They are not for diagnostic, therapeutic, cosmetic, or human and animal uses. They are not sold to individuals. Additional restrictions may apply.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. CATEGORIES APIs and Bioactives > Antivirals, HIV Protease Inhibitors
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