67227-56-9 Fenoldopam AKSci I745
 
 
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  I745    AKSci Reference Standard
Fenoldopam
, 98% (HPLC), powder
 



IDENTITY
CAS Number:67227-56-9
MDL Number:MFCD00865806
MF:C16H16ClNO3
MW:305.76
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:210-214°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):Dopamine agonist

REVIEW

 Fenoldopam is a rapid-acting vasodilator. It is an agonist for D1-like dopamine receptors and binds with moderate affinity to alpha-2-adrenoceptors. It has no significant affinity for D2-like receptors, alpha-1 and beta--adrenoceptors, 5HT1 and 5HT2 receptors, or muscarinic receptors. Fenoldopam is a racemic mixture with the R-isomer responsible for the biological activity. The R-isomer has approximately 250-fold higher affinity for D1-like receptors than does the S-isomer. In non-clinical studies, fenoldopam had no agonist effect on presynaptic D2-like dopamine receptors, or alpha- or beta- -adrenoceptors, nor did it affect angiotensin-converting enzyme activity. Fenoldopam may increase norepinephrine plasma concentration.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Danger

Hazard Statements
H302; H317; H319; H334

Precautionary Statements
P261; P264; P270; P272; P280; P285; P301+P312; P302+P352; P304+P341; P305+P351+P338; P321; P330; P333+P313; P337+P313; P342+P311; P363; P501


RELATED PRODUCTS
K106Fenoldopam methanesulfonate
I745Fenoldopam

Current as of October 1, 2022

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Dopamine Agonists


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