50700-72-6 Vecuronium bromide AKSci H858
 
 
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  H858    
Vecuronium bromide
, 98% (HPLC)
 
1-[(2beta,3alpha,5alpha,16beta,17beta)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-piperidinium bromide




IDENTITY
CAS Number:50700-72-6
MDL Number:MFCD00867762
MF:C34H57N2O4.Br
MW:637.73
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Spectra:HPLC, Polarimetry
Physical Form:White to light yellow powder
Melting Point:227-234°C
Optical Rotation:+31.0 to +34.0° (c=1, 0.05mol/L HCl)
Long-Term Storage:Store long-term at -20°C

BIOLOGICAL INFO
Solubility:Soluble in water
Application(s):Non-depolarizing neuromuscular blocking agent

REVIEW

 Vecuronium is a bisquaternary nitrogen compound that acts by competitively binding to nicotinic cholinergic receptors. The binding of vecuronium decreases the opportunity for acetylcholine to bind to the nicotinic receptor at the postjunctional membrane of the myoneural junction. As a result, depolarization is prevented, calcium ions are not released and muscle contraction does not occur.

REFERENCES
[1]Yiu, K. C. H.; Chromatographia 2004, V59(Suppl. 1), PS45-S50
[2] Thieme, Detlef; Analytica Chimica Acta 2003, V492(1-2), P171-186

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H302

Precautionary Statements
P264; P270; P301+P312; P330; P501


RELATED PRODUCTS
H858Vecuronium bromide
H896Rocuronium bromide

Current as of June 24, 2019


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CATEGORIES

 APIs and Bioactives > AChR Antagonists


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