4803-74-1 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone AKSci F742
 
 
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  F742    AKSci Bulk Reagent
5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone, 98% (HPLC)
 
5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one
IDENTITY
CAS Number:4803-74-1
MDL Number:MFCD08458868
MF:C17H15NO3
MW:281.31
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:210-211°C
Density:1.255
Refractive Index:1.63
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):Intermediate
Form:Free Base

REVIEW
 Purcursor and impurity of Donepezil

REFERENCES
[1]Gurusamy, Renugadevi; Roy, Mita; Shanmuganathan, Ramasubramanian; Jagtap, Ashutosh; Hariharan, Sivaramakrishnan; Mishra, Sushil Kumar; Wankhede, Karuna; A process for preparation of intermediates of donepezil hydrochloride. PCT Int. Appl. (2012), WO 2012131540 A1 20121004.
[2] Reddy, Manne Satyanarayana; Eswaraiah, Sajja; Thippannachar, Mathad Vijayavitthal; Chandrashekar, Elati Ravi Rama; Kumar, Podichetty Anil; Kumar, Kolla Naveen; Process for preparation of donepezil. U.S. Pat. Appl. Publ. (2004), US 20040143121 A1 20040722.
[3] Lensky, Stephen; Process and catalysts for the hydrogenation production of 1-benzyl-4-(indan-1-onyl)piperidines from pyridinium salts. Eur. Pat. Appl. (1996), EP 711756 A1 19960515.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

RELATED PRODUCTS
F7425,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone
I9025,6-Dimethoxy-2-(piperidin-4-yl)methyl-indan-1-one HCl
P1005,6-Dimethoxy-2-(piperidin-4-yl)methylindan-1-one

Current as of December 26, 2024


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