219861-08-2 Escitalopram oxalate AKSci F497
 
 
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  F497    AKSci Bulk Reagent
Escitalopram oxalate
, 99% (HPLC)
 
S-(+)-Citalopram oxalate
S-(+)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate




IDENTITY
CAS Number:219861-08-2
MDL Number:MFCD06407826
MF:C22H23FN2O5
MW:414.43
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:147-155°C
Optical Rotation:+10 to +12° (c=1, MeOH)
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):Selective serotonin reuptake inhibitor (SSRI)

REVIEW

 Escitalopram is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is approved by the U.S. Food and Drug Administration (FDA) for the treatment of adults and children over 12 years of age with major depressive disorder and generalized anxiety disorder. Escitalopram is the (S)-stereoisomer (enantiomer) of the earlier Lundbeck drug citalopram, hence the name escitalopram. Escitalopram is noted for its high selectivity with serotonin reuptake inhibition. Its side effects are normal for the SSRI class.

REFERENCES
[1]Cipriani, A; Furukawa TA; Salanti G; Geddes JR; Higgins JP; Churchill R; Watanabe N; Nakagawa A; Omori IM; McGuire H; Tansella M; Barbui C (2009 February 28). Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis. Lancet 373 (9665): 746-58. PMID 19185342.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


RELATED PRODUCTS
F497Escitalopram oxalate
K750Citalopram hydrobromide
X4935(R)-Citalopram oxalate

Current as of February 2, 2025


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CATEGORIES

 APIs and Bioactives > Antidepressants


PubChem