5451-09-2 5-Aminolevulinic acid hydrochloride AKSci F147
 
 
Loading Please Wait...
  F147    AKSci Bulk Reagent
5-Aminolevulinic acid hydrochloride, 98% (HPLC)
 
5-Amino-4-oxopentanoic acid hydrochloride
5-Aminolaevulinic acid hydrochloride
Levulan
more..
IDENTITY
CAS Number:5451-09-2
MDL Number:MFCD00012869
MF:C5H10ClNO3
MW:167.59
EINECS:226-679-5
BRN:3690651
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:154-162°C
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 34mg/mL; H2O: 34mg/mL; EtOH: 6mg/mL
Application(s):Intermediate in heme biosynthesis
Form:HCl salt

REVIEW
 5-Aminolevulinic acid hydrochloride is used as a photosensitizer for photodynamic detection and therapy for actinic keratosis. It is biosynthesized from succinyl-CoA and glycine and is the first compound in the porphyrin synthesis pathway. It elicits synthesis and accumulation of fluorescent porphyrins in epithelia and neoplastic tissues.

REFERENCES
[1]Herdeis, Claus; Dimmerling, Anna A three-step synthesis of epsilon-aminolevulinic acid Archiv der Pharmazie (Weinheim, Germany) (1984), 317(4), 304-6.
[2] Kawakami, Hiroshi; Ebata, Takashi; Matsushita, Hajime A new synthesis of 5-aminolevulinic acid Agricultural and Biological Chemistry (1991), 55(6), 1687-8.
[3] Matsumura, Yoshihiro; Takeshima, Yo-ichiro; Okita, Hideki A convenient method for introducing oxo group into the beta-position of cyclic amines and its application to synthesis of epsilon-aminolevulinic acid Bulletin of the Chemical Society of Japan (1994), 67(1), 304-6.
[4] Nokes B, Apel M, Jones C, Brown G, Lang JE.Aminolevulinic acid (ALA): photodynamic detection and potential therapeutic applications.J Surg Res. 2013 May;181(2):262-71.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

RELATED PRODUCTS
1451AA5-Amino-4-oxopentanoic acid
F1475-Aminolevulinic acid hydrochloride

Current as of May 31, 2025


Download SDS Request COA

All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
 APIs and Bioactives > Dermatology


PubChem
  @PubMed