9004-54-0 Dextran 40, MW ca 40,000 AKSci B997
 
 
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  B997    
Dextran 40, MW ca 40,000
 
Dextran 40




IDENTITY
CAS Number:9004-54-0
MDL Number:MFCD00130935
MF:(C6H16O5)n
EINECS:232-677-5
SPECIFICATIONS & PROPERTIES
Physical Form (at 20°C):White powder
Melting Point:260-280°C
Optical Rotation:+180° to +195° (c=6, H2O)
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW

 Dextran is a complex branched glucan composed of chains of varying lengths, from 3 to 2000 kilodaltons. It is used as a replacement for blood loss, a plasma substitute, an antithrombotic, to reduce blood viscosity, to improve blood flow and as a volume expander in anemia. The straight chain consists of a-1,6 glycosidic linkages between glucose molecules, while branches begin from a-1,3 linkages. Dextran is synthesized from sucrose by certain lactic-acid bacteria, the best-known being Leuconostoc mesenteroides and Streptococcus mutans. Dental plaque is rich in dextrans. Dextran was first discovered by Louis Pasteur as a microbial product in wine.

REFERENCES
[1]Stadil F.Dextran''s anthrombotic properties. A review. Ugeskr Laeger. 1970 Sep 24;132(39):1813-6.
[2] Broukal Z. Significance of microbial polysaccharides in the pathogenesis of dental caries. Review]. Cesk Epidemiol Mikrobiol Imunol. 1973 Mar;22(2):95-110.
[3] Sidebotham RL. Dextrans. Adv Carbohydr Chem Biochem. 1974;30:371-444.
[4] Data JL, Nies AS.Drugs five years later: dextran 40. Ann Intern Med. 1974 Oct;81(4):500-4.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


RELATED PRODUCTS
B997Dextran 40, MW ca 40,000
H979Dextran 70, MW ca 70,000

Current as of December 4, 2021


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CATEGORIES

 APIs and Bioactives > Antiplatelets, Thrombosis
 Carbohydrates > Polysaccharides
 Carbohydrates > Polysaccharides


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