Among click chemistry reactions, the Huisgen 1,3-dipolar cycloaddition of azides to alkynes to give 1,2,3-triazoles is, as Dr. Sharpless called it, "the cream of the crop".
AK Scientific stocks unique alkynes and azides AMT, suited both for the Huisgen click reaction and for Suzuki coupling. AMT Click Chemistry Fact Sheet
Kolb, H. C.; Finn, M. G.; Sharpless, K. B. Click Chemistry: Diverse Chemical Function from a Few Good Reactions. Angew. Chem., Int. Ed.2001,40, 2004-2021.
Tron, G. C.; Pirali, T.; Billington, R. A.; Canonico, P. L.; Sorba, G.; Genazzani, A. A. Click Chemistry Reactions in Medicinal Chemistry: Applications of the 1,3-dipolar Cycloaddition between Azides and Alkynes. Med. Res. Rev.2007,28, 278-308.
AMTB503: White, J. R.; Price, G. J.; Schiffers, S.; Raithby, P. R.; Plucinski, P. K.; Frost, C. G. A Modular Approach to Catalytic Synthesis Using a Dual-functional Linker for Click and Suzuki Coupling Reactions. Tetrahedron Lett.2010,51, 3913-3917.
AMTB515: Mulla, K.; Dongare, P.; Zhou, N.; Chen, G.; Thompson, D. W.; Zhao, Y. Highly Sensitive Detection of Saccharides under Physiological Conditions with Click Synthesized Boronic Acid-Oligmer Fluorophores. Org. Biomol. Chem.2011,9, 1332-1336.
AMTB514: Molander, G. A.; Ham, J. Synthesis of Functionalized Organotrifluoroborates via the 1,3-Dipolar Cycloaddition of Azides. Org. Lett.2006,8, 2767-2770.
Among click chemistry reactions, the Huisgen 1,3-dipolar cycloaddition of azides to alkynes to give 1,2,3-triazoles is, as Dr. Sharpless called it, "the cream of the crop".
AMT Click Chemistry Fact Sheet
