REVIEW C-Alkylation of the piperazine in AKSci cat# Y0432 results in increased DPP8 selectivity over DPP9.
REFERENCES
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Van Goethem, S., Matheeussen, V., Joossens, J., Lambeir, A.-M., Chen, X., De Meester, I., Haemers, A., Augustyns, K., and Van der Veken, P. (2011) Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal? J. Med. Chem. 54, 5737-5746.
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