873054-44-5 Ivacaftor (VX-770) AKSci X7565
 
 
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  X7565    
Ivacaftor (VX-770), 99% (HPLC), powder
 
VX-770
IDENTITY
CAS Number:873054-44-5
MDL Number:MFCD17171361
MF:C24H28N2O3
MW:392.49
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:292-295°C
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO
Application(s):Potentiator of CFTR targeting G551D-CFTR and F508del-CFTR
Form:Free Base
Research Area:Cancer

REVIEW
 Ivacaftor (VX-770) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM in fisher rat thyroid cells, respectively.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of December 26, 2024


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