[1236699-92-5] Pimasertib AKSci X7392
 
 
Loading Please Wait...
  X7392    
Pimasertib
, 98% (HPLC)
 
AS-703026, N-[(2S)-2,3-Dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide




IDENTITY
CAS Number:[1236699-92-5]
MDL Number:MFCD16660676
MF:C15H15FIN3O3
MW:431.2
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Available Spectra:NMR, MS, HPLC, Polarimetry
Physical Form:Light yellow powder
Melting Point:164-169°C
Optical Rotation:-16° ~ -25° (c=0.1, DMSO)
Density:1.769
Refractive Index:1.684
Long-Term Storage:Store long-term at -20°C

BIOLOGICAL INFO
Solubility:DMSO 86 mg/mL
Application(s):MEK1/2 inhibitor
Form:Free base

REVIEW

 Pimasertib (AS703026) is a highly selective and potent non-competitive inhibitor of MEK1/2 with IC50 of 5-11 nM.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of May 24, 2017


Download SDS

CATEGORIES

 APIs and Bioactives >


PubChem