362-07-2 2-Methoxyestradiol AKSci X5011
 
 
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  X5011    AKSci Reference Standard
2-Methoxyestradiol, 98% (HPLC)
 
3,17β-Dihydroxy-2-methoxy-1,3,5(10)-estratriene, 2,3,17β-Trihydroxy-1,3,5(10)-estratriene 2-methyl ether, 1,3,5(10)-Estratriene-2,3,17-triol 2-methyl ether, 2-Hydroxyestradiol 2-methyl ether
IDENTITY
CAS Number:362-07-2
MDL Number:MFCD00010489
MF:C19H26O3
MW:302.41
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:186-190°C
Optical Rotation:+104° (c=55mg/10ml of CHCL3)
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
UN #:UN2811
Hazard Class:6.1; Poison
Packing Group:III
A hazmat fee may apply to certain package sizes and shipment methods. Please check pricing table for an indicator of applicable hazmat fees.

BIOLOGICAL INFO
Solubility:DMSO: 10 mg/mL; ethanol: 10 mg/mL; H2O: insoluble
Application(s):Tubulin polymerization inhibitor
Form:Free Base
Research Area:pulmonary hypertension

REVIEW
 2-Methoxyestradiol (2-ME) is a potent inhibitor of endothelial cell proliferation and angiogenesis. A major estradiol metabolite, it has little affinity for classical estrogen receptors.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Danger

Hazard Statements
H301+H311+H331; H315; H319; H335; H350; H360; H372; H410

Precautionary Statements
P201; P202; P260; P264; P270; P271; P273; P280; P301+P310; P302+P352; P304+P340; P305+P351+P338; P308+P313; P322; P330; P332+P313; P337+P313; P361; P391; P403+P233; P405; P501

Current as of July 16, 2025

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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