126784-99-4 Ulipristal acetate AKSci X4788
 
 
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  X4788    AKSci Reference Standard
Ulipristal acetate
, 98% (HPLC)
 
17-Acetoxy-11-(4-N,N-dimethylaminophenyl)pregna-4,9-diene-3,20-dione




IDENTITY
CAS Number:126784-99-4
MDL Number:MFCD00899035
MF:C30H37NO4
MW:475.63
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:183-185°C
Optical Rotation:165 to +185°, (c=1 in dichloromethane)
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: soluble 5 mg/mL, clear (warmed)

REVIEW

 Ulipristal acetate is a novel selective progesterone receptor modulator (SPRM) for the treatment of benign gynecological conditions such as uterine myoma. Ulipristal acetate is used as an emergency contraceptive in women. A single dose of 30 mg ulipristal acetate has recently been proposed for the emergency contraception use up to 120 h of unprotected intercourse with similar side effect profiles as levonorgestrel.

REFERENCES
[1]Jadav SP, Parmar DM. Ulipristal acetate, a progesterone receptor modulator for emergency contraception. J Pharmacol Pharmacother. 2012 Apr;3(2):109-11.
[2] Talaulikar VS, Manyonda IT. Ulipristal acetate: a novel option for the medical management of symptomatic uterine fibroids. Adv Ther. 2012 Aug;29(8):655-63.
[3] Nallasamy S, Kim J, Sitruk-Ware R, et al. Ulipristal Blocks Ovulation by Inhibiting Progesterone Receptor-Dependent Pathways Intrinsic to the Ovary. Reprod Sci. 2012 Sep 25.
[4] Kim, Hyun K.; WO 2004078709 A2 2004

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of October 1, 2022

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Progesterone Receptor Modulators


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