6164-67-6 Pseudopelletierine oxime AKSci X3279
 
 
Loading Please Wait...
  X3279    AKSci Bulk Reagent
Pseudopelletierine oxime, 98% (HPLC)
 
N-(9-Methyl-9-azabicyclo[3.3.1]nonan-3-ylidene)hydroxylamine
IDENTITY
CAS Number:6164-67-6
MDL Number:MFCD03755545
MF:C9H16N2O
MW:168.24
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:126-130°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):5-HT3 antagonist

REVIEW
 Pseudopelletierine oxime, the oxime of 3-tropinone, is a key intermediate in the synthesis of Dolasetron (dolasetron mesilate) a 5-HT3 antagonist.

REFERENCES
[1]Putney, Blake F.; Soine, Taito O.; A synthesis of pseudopelletierine, Journal of the American Pharmaceutical Association (1912-1977) (1955), 44, 17-22.
[2] Hadley, Michael Stewart; King, Francis David Azabicycloalkyl derivatives and pharmaceutical compositions containing them. Eur. Pat. Appl. (1980), EP 13138 A1 19800709.
[3] Smith, Gillian Elizabeth. Process for the production of aminoazabicycloalkanes from oximes. PCT Int. Appl. (1996), WO 9603401 A2 19960208.
[4] Vernekar, Sanjeev Kumar V.; Hallaq, Hasan Y.; Clarkson, Guy; Thompson, Andrew J.; Silvestri, Linda; Lummis, Sarah C. R.; Lochner, Martin Toward Biophysical Probes for the 5-HT3 Receptor: Structure-Activity Relationship Study of Granisetron Derivatives. Journal of Medicinal Chemistry (2010), 53(5), 2324-2328.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of December 21, 2024


Download SDS Request COA

All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
 APIs and Bioactives > Alkaloids


PubChem
  @PubMed