REVIEW Cediranib (Recentin and AZD2171), is a potent inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases, developed by AstraZeneca as a possible anti-cancer chemotherapeutic agent against a variety of solid malignancies for oral administration. The drug has shown promising, in preclinical models and in clinical trials. Its pharmacokinetics allow for a convenient once-daily administration. Clinical trials are still evaluating the role of cediranib in combination chemotherapy with cytotoxic agents.
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