[89-82-7] (R)-(+)-Pulegone AKSci W2906
 
 
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  W2906    
(R)-(+)-Pulegone
, 98% (HPLC)
 
(+)-Pulegone
(R)-p-Menth-4(8)-en-3-one
(R)-2-Isopropylidene-5-methylcyclohexanone
more..




IDENTITY
CAS Number:[89-82-7]
MDL Number:MFCD00063000
MF:C10H16O
MW:152.23
EINECS:201-943-2
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Available Spectra:GCMS, GC
Physical Form:Colorless to yellow clear liquid
Boiling Point:224°C
Flash Point:82°C
Optical Rotation:+18° - +24° (7.7g/100mL, CHCl3)
Density:0.937
Refractive Index:1.486
Long-Term Storage:Store at room temperature
UN #:NA1993
Hazard Class:Comb liq
Packing Group:III

BIOLOGICAL INFO
Solubility:H2O: insoluble; EtOH

REVIEW

 Pulegone is a naturally occurring organic compound obtained from the essential oils of a variety of plants such as Nepeta cataria (catnip), Mentha piperita, and pennyroyal. It is classified as a monoterpene.

REFERENCES
[1]Auerbach SS, Elmore SA, Bishop JB, Bucher JR, Chan PC, Chhabra RS, Foster PM, Herbert RA, Hooth MJ, King-Herbert AP, Kissling GE, Malarkey DE, Roycroft JH, Sanders JM, Smith CS, Travlos GS, Walker NJ, Witt KL, Hejtmancik MR, Sells DM, Skowronek AJ, Toft JD 2nd, Hamlin MH 2nd, Brix AE, Hard GC, Kolenda-Roberts HM, Peckham JC, Wolfe GW, Seung HS, Brecher S, Iyer S, Tharakan VS, Morrison JP, Elmore SA, Flake GP, Hard GC, Kolenda-Roberts HM, Malarkey DE, Maronpot RR, Peckham JC, Morrison JP, Belpoggi F, Brix AE, Elmore SA, Flake GP, Hard GC, Herbert RA, Malarkey DE, Maronpot RR, Wakamatsu N, Crockett PW, Betz LJ, McGowan KP, Gunnels SR, Coker KK, Harper LM, Serbus DC (2011). Toxicology and carcinogenesis studies of pulegone (CAS No. 89-82-7) in F344/N rats and B6C3F1 mice (gavage studies). Natl Toxicol Program Tech Rep Ser. (563):1-201. PMID 21921962.
[2] de Cerqueira SV, Gondim AN, Roman-Campos D, Cruz JS, Passos AG, Lauton-Santos S, Lara A, Guatimosim S, Conde-Garcia EA, de Oliveira ED, de Vasconcelos CM (2011). R(+)-pulegone impairs Ca²+ homeostasis and causes negative inotropism in mammalian myocardium. Eur J Pharmacol. 672(1-3):135-42. PMID 22004607.
[3] Shimizu, Hideo; Synlett 2009, (19), P3143-3146

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H227; H302; H351; H412

Precautionary Statements
P201; P202; P210; P264; P270; P273; P280; P301+P312+P330; P308+P313; P308+P313; P403+P235; P405P501


Current as of December 15, 2017


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CATEGORIES

 APIs and Bioactives > Natural Products


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