27548-93-2 Baccatin III AKSci W1317
 
 
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  W1317    AKSci Reference Standard
Baccatin III
, 98% (HPLC)
 



IDENTITY
CAS Number:27548-93-2
MDL Number:MFCD00153921
MF:C31H38O11
MW:586.6
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Spectra:LCMS, HPLC
Physical Form:White powder
Melting Point:229-234°C
Refractive Index:1.5455-1.5475
Long-Term Storage:Store long-term at 2-8°C

REVIEW

 Baccatin III is an isolate of the Pacific yew tree (Taxus brevifolia) and related species. It is a precursor to the cancer drug paclitaxel.

REFERENCES
[1]Magri, Neal F.; Kingston, David G. I.; Jitrangsri, Chote; Piccariello, Thomas Modified taxols. 3. Preparation and acylation of baccatin III Journal of Organic Chemistry (1986), 51(16), 3239-42.
[2] Holton, Robert A.; Somoza, Carmen; Kim, Hyeong B.; Shindo, Mitsuru; Biediger, Ronald J.; Boatman, P. Douglas; Smith, Chase; Liang, Feng; Murthi, Krishna Synthesis of taxol and its derivatives PCT Int. Appl. (1995), WO 9503265 A1 19950202.
[3] Danishefsky, Samuel J.; Masters, John J.; Young, Wendy B.; Link, J. T.; Snyder, Lawrence B.; Magee, Thomas V.; Jung, David K.; Isaacs, Richard C. A.; Bornmann, William G.; et al. Total Synthesis of Baccatin III and Taxol Journal of the American Chemical Society (1996), 118(12), 2843-59.
[4] Shiina, Isamu; Iwadare, Hayato; Sakoh, Hiroki; Hasegawa, Masatoshi; Tani, Yu-ichirou; Mukaiyama, Teruaki A new method for the synthesis of baccatin III Chemistry Letters (1998), (1), 1-2.

GHS

Pictograms

Signal Word
Danger

Hazard Statements
H315; H319; H335; H350

Precautionary Statements
P201; P261; P305+P351+P338; P308+P313


RELATED PRODUCTS

Current as of October 19, 2019

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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For research use only. Not for diagnostic or therapeutic use.
Not for human use.


CATEGORIES

 APIs and Bioactives > Chemotherapeutics


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