1477-19-6 (2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone AKSci W0011
 
 
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  W0011    
(2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone
, 98% (HPLC)
 



IDENTITY
CAS Number:1477-19-6
MDL Number:MFCD00867417
MF:C17H14O3
MW:266.29
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:124-128°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):Uric Acid Transporter 1 (hURAT1) and human fatty acid binding protein 4

REVIEW

 Benzarone is a thrombolytic drug used as a vasoprotective agent.Initially used for the treatment of gout and now used in antivaricose therapy. Benzarone has been recently shown to be an inhibitor of Uric Acid Transporter 1 (hURAT1) and human fatty acid binding protein 4.

REFERENCES
[1]Marmo, Emilio. Pharmacodynamic characteristics of benzarone, 2-ethyl-(p-hydroxybenzoyl)benzofuran, Archivio Italiano di Scienze Farmacologiche (1965), 15(1-2), 73-5.
[2] Chaillet, Francois; Barchewitz, G.; Charlier, Robert; Guilbert, A.; Colot, M.; Deltour, G. Benzofurans. XLIII. Angiotropic, antiinflammatory, and fibrinolytic properties of benzarone Arzneimittel-Forschung (1970), 20(3), 358-63.
[3] Chaillet, F.; Barchewitz, G.; Charlier, R.; Guilbert, A.; Colot, M.; Deltour, G. Angiotrophic, antiinflammatory, and fibrinolytic properties of benzarone Gazzetta Medica Italiana (1971), 130(2), 75-85.
[4] Brotelle, R. The antithrombotic properties of Fragivix Ergebnisse der Angiologie (1976), 11, 83-95.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302; H413

Precautionary Statements
P264; P270; P273; P301+P312; P330; P501


Current as of May 28, 2024


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