69004-04-2 Toltrazuril sulfone AKSci V1744
 
 
Loading Please Wait...
  V1744    AKSci Reference Standard
Toltrazuril sulfone
, 98% (HPLC)
 
1-Methyl-3-{3-methyl-4-[4-(trifluoromethylsulfonyl)phenoxy]phenyl}-1,3,5-triazine-2,4,6(1H,3H,5H)-trione
Toltrazuril




IDENTITY
CAS Number:69004-04-2
MDL Number:MFCD09263475
MF:C18H14F3N3O6S
MW:457.38
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Spectra:NMR, FT-IR, LCMS, HPLC
Physical Form:White powder
Melting Point:241-246°C
Long-Term Storage:Store at room temperature

REVIEW

 Ponazuril is a triazinedione drug approved for the treatment of equine protozoal myeloencephalitis caused by Sarcocystis neurona. It has also been used in smaller animals against coccidia.

REFERENCES
[1]Ponazuril is a triazinedione drug currently approved for the treatment of equine protozoal myeloencephalitis caused by Sarcocystis neurona. More recently, veterinarians have been preparing a formulary version of the medication for use in small animals such as cats and dogs against coccidia, an intestinal parasite.
[2] Kennedy, Thomas J. Triazineone compounds for treating diseases due to Sarcosystis, Neospora and Toxoplasma PCT Int. Appl. (2000), WO 2000037063 A2 20000629.
[3] Gottstein B, Eperon S, Dai WJ, Cannas A, Hemphill A, Greif G. Efficacy of toltrazuril and ponazuril against experimental Neospora caninum infection in mice. Parasitol Res. 2001 Jan;87(1):43-8.
[4] Kritzner S, Sager H, Blum J, Krebber R, Greif G, Gottstein B.An explorative study to assess the efficacy of toltrazuril-sulfone (ponazuril) in calves experimentally infected with Neospora caninum. Ann Clin Microbiol Antimicrob. 2002 Oct 18;1:4.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of May 23, 2019

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


Download SDS

CATEGORIES

 APIs and Bioactives > Antiparasitics, Veterinary


PubChem
  @PubMed