82640-04-8 Raloxifene hydrochloride AKSci V1611
 
 
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  V1611    AKSci Reference Standard
Raloxifene hydrochloride
, 99% (HPLC)
 
Keoxifene hydrochloride
[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone hydrochloride
LY 156758




IDENTITY
CAS Number:82640-04-8
MDL Number:MFCD01938233
MF:C28H28ClNO4S
MW:510.04
BRN:6036780
SPECIFICATIONS & PROPERTIES
Purity:99% (HPLC)
Spectra:LCMS, NMR, HPLC
Physical Form:Off-white to light yellow powder or crystalline powder
Melting Point:253-268°C
Long-Term Storage:Store at room temperature

BIOLOGICAL INFO
Application(s):Estrogen agonist/antagonist
Form:HCl salt

REVIEW

 An oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women.

REFERENCES
[1]Hummel CW, Geiser AG, Bryant HU, Cohen IR, Dally RD, Fong KC, Frank SA, Hinklin R, Jones SA, Lewis G, McCann DJ, Rudmann DG, Shepherd TA, Tian H, Wallace OB, Wang M, Wang Y, Dodge JA (2005). A selective estrogen receptor modulator designed for the treatment of uterine leiomyoma with unique tissue specificity for uterus and ovaries in rats. J Med Chem. 48(22):6772-5. PMID 16250633.
[2] Yuan J, Johnson RL, Huang R, Wichterman J, Jiang H, Hayton K, Fidock DA, Wellems TE, Inglese J, Austin CP, Su XZ (2009). Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nat Chem Biol. 5(10):765-71. PMID 19734910.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of August 23, 2019

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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For research use only. Not for diagnostic or therapeutic use.
Not for human use.


CATEGORIES

 APIs and Bioactives > Estrogen Receptor Modulators


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