60414-06-4 Amiprilose hydrochloride AKSci V0471
 
 
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  V0471    
Amiprilose hydrochloride, 95% (HPLC)
 
1,2-O-Isopropylidene-3-O-[3'-(N,N-dimethylamino)propyl]-alpha-D-glucofuranose hydrochloride
IDENTITY
CAS Number:60414-06-4
MDL Number:MFCD00133070
MF:C14H27NO6.HCl
MW:341.83
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95% (HPLC)
Physical Form (at 20°C):Liquid
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):Adjuvant; NSAID; Antiviral Agent
Form:HCl salt

REVIEW
 Amiprilose hydrochloride is a synthetic hexose sugar used for the treatment of rheumatoid arthritis. It has been shown to have regulatory effects on cytokines, an immunoregulatory effect which supports the potential of this drug as a therapeutic agent for the treatment of inflammatory arthritis.

REFERENCES
[1]Linhardt, R. J.; Baenziger, N. C.; Ronsen, B. Structure of amiprilose hydrochloride, a novel anti-inflammatory agent. Journal of Pharmaceutical Sciences. (1990) 79(2): 158-62.
[2] Tripathi, R. P.; Singh, V.; Khan, A. R.; Bhaduri, A. P.; Saxena, G.; Chandra, K. Syntheses and antiviral activities of 3-O-(aminoalkyl)-1,2-O-isopropylidene-a-D-gluco(xylo)furanoses. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry. (1995) 34B(9): 791-5.
[3] Young M R. Modulation of eicosanoid biosynthesis and inhibition of substrate availability for phospholipase A2 by a modified hexose sugar, amiprilose hydrochloride. Prostaglandins. (1990) 40(1): 35-49.
[4] Gordon, Paul Therapeutic carbohydrate derivatives, Ger. Offen. (1975), DE 2455026 A1 19750703.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of December 26, 2024


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