13870-90-1 Coenzyme B12 AKSci V0102
 
 
Loading Please Wait...
  V0102    AKSci Reference Standard
Coenzyme B12
, 97% (HPLC)
 
5'-Deoxyadenosylcobalamin




IDENTITY
CAS Number:13870-90-1
MDL Number:MFCD00135609
MF:C72H100CoN18O17P
MW:1579.58
EINECS:237-627-6
BRN:4122932
SPECIFICATIONS & PROPERTIES
Purity:97% (HPLC)
Spectra:FT-IR, LCMS, HPLC
Physical Form:Dark red powder
Long-Term Storage:Store long-term at -20°C

REVIEW

 Coenzyme B12 is one of the active forms of vitamin B12. As a nutritional supplement, it is available in tableted form, but not in injectable form. It has been used therapeutically to treat vitamin B12 deficiency. Vitamin B12 derivatives are also used to treat cyanide poisoning, and hereditary deficiency of transcobalamin II. Vitamin B12 consists of a class of chemically related compounds (vitamers), all of which have vitamin activity. It contains the biochemically rare element cobalt.

REFERENCES
[1]Gruber, Karl; Puffer, Barbara; Kraeutler, Bernhard. Vitamin B12-derivatives - enzyme cofactors and ligands of proteins and nucleic acids. Chemical Society Reviews. (2011) 40(8): 4346-4363.
[2] Marsh, E. Neil G.; Melendez, Gabriel D. Roman Adenosylcobalamin enzymes: Theory and experiment begin to converge. Biochimica et Biophysica Acta, Proteins and Proteomics. (2012) 1824(11): 1154-1164.
[3] Brown, Kenneth L. The enzymatic activation of coenzyme B12. Dalton Transactions. (2006) (9): 1123-1133.
[4] Roth J R; Lawrence J G; Bobik T A Cobalamin (coenzyme B12): synthesis and biological significance Annual review of microbiology (1996), 50, 137-81.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of July 9, 2020

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


Download SDS

For research use only. Not for diagnostic or therapeutic use. Not for human use. AK Scientific, Inc. does not sell to individuals. If you are a first-time customer, please email for review at least two official business documents issued by your local jurisdiction, state/province, or country.


CATEGORIES

 APIs and Bioactives > Vitamins


PubChem