13870-90-1 Coenzyme B12 AKSci V0102
 
 
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  V0102    AKSci Reference Standard
Coenzyme B12
, 97% (HPLC)
 
5'-Deoxyadenosylcobalamin

Structure N/A

IDENTITY
CAS Number:13870-90-1
MDL Number:MFCD00135609
MF:C72H100CoN18O17P
MW:1579.58
EINECS:237-627-6
BRN:4122932
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:97% (HPLC)
Physical Form (at 20°C):Solid
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW

 Coenzyme B12 is one of the active forms of vitamin B12. As a nutritional supplement, it is available in tableted form, but not in injectable form. It has been used therapeutically to treat vitamin B12 deficiency. Vitamin B12 derivatives are also used to treat cyanide poisoning, and hereditary deficiency of transcobalamin II. Vitamin B12 consists of a class of chemically related compounds (vitamers), all of which have vitamin activity. It contains the biochemically rare element cobalt.

REFERENCES
[1]Gruber, Karl; Puffer, Barbara; Kraeutler, Bernhard. Vitamin B12-derivatives - enzyme cofactors and ligands of proteins and nucleic acids. Chemical Society Reviews. (2011) 40(8): 4346-4363.
[2] Marsh, E. Neil G.; Melendez, Gabriel D. Roman Adenosylcobalamin enzymes: Theory and experiment begin to converge. Biochimica et Biophysica Acta, Proteins and Proteomics. (2012) 1824(11): 1154-1164.
[3] Brown, Kenneth L. The enzymatic activation of coenzyme B12. Dalton Transactions. (2006) (9): 1123-1133.
[4] Roth J R; Lawrence J G; Bobik T A Cobalamin (coenzyme B12): synthesis and biological significance Annual review of microbiology (1996), 50, 137-81.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of September 30, 2022

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Vitamins


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