681847-92-7 ML 00253764 Hydrochloride AKSci SYN5200
 
 
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  SYN5200    
ML 00253764 Hydrochloride, 98%
 
ML-00253764
IDENTITY
CAS Number:681847-92-7
MDL Number:MFCD28133377
MF:C18H18BrFN2O.HCl
MW:413.71
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98%
Physical Form (at 20°C):Solid
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:10 mM in water, 100 mM in DMSO

REVIEW
 Non-peptide, melanocortin MC4 receptor antagonist (IC50 values are 0.32, 0.81 and 2.12 μM for MC4, MC3 and MC5 receptors respectively). Decreases cAMP accumulation in HEK-293 cells expressing the MC4 receptor. Increases food intake and reduces loss of lean body mass in tumor bearing mice. Brain penetrant.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of August 2, 2025


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