1166393-85-6 PF4618433 AKSci SYN1163
 
 
Loading Please Wait...
  SYN1163    
PF4618433
, 98%
 
PF-4618433




IDENTITY
CAS Number:1166393-85-6
MDL Number:MFCD25977104
MF:C24H27N7O2
MW:445.52
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98%
Long-Term Storage:Store long-term at -20°C
HAZARDOUS MATERIALS INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:20 mM in DMSO
Application(s):PYK2 - FAK

REVIEW

 PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796. In the functional osteogenesis assays, cultures treated with increasing concentrations of PF-4618433 starting at day 1 and maintained throughout showed a dose-dependent increases in both alkaline phosphatase activity and mineralization

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of May 7, 2021


Download SDS

For research use only. Not for diagnostic or therapeutic use. Not for human use. AK Scientific, Inc. does not sell to individuals. If you are a first-time customer, please email for review at least two official business documents issued by your local jurisdiction, state/province, or country.