1258296-60-4 RO495 AKSci SYN1128
 
 
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  SYN1128    
RO495
, >95%
 



IDENTITY
CAS Number:1258296-60-4
MDL Number:MFCD21364479
MF:C17H14Cl2N6O
MW:389.24
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>95%
Long-Term Storage:Store at room temperature
HAZARDOUS MATERIALS INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO 112 mg/mL, Water 1mg/mL, Ethanol 4mg/mL
Application(s):TYK2

REVIEW

 RO495 is a very potent TYK2 inhibitor with a IC50 of 1.5nM on TYK2 as tested in cell-based pharmacological assays including the compound-mediated effects on STAT5 phosphorylation in Set-2 lysates or IL-12 stimulation of NK92 using the Meso Scale Discovery (MSD) technology.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of January 18, 2021


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