284461-73-0 Sorafenib AKSci SYN1082
 
 
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  SYN1082    
Sorafenib
, >99%
 
Nexavar
BAY43-9006




IDENTITY
CAS Number:284461-73-0
MDL Number:MFCD06411450
MF:C21H16ClF3N4O3
MW:464.82
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>99%
Physical Form (at 20°C):Solid
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO 127mg/mL, Ethanol 1mg/mL
Application(s):ARaf - CRaf - BRaf

REVIEW

 Sorafenib is a multi-kinase inhibitor targeting a number of serine/threonine and receptor tyrosine kinases. It inhibits Raf-1, B-Raf and VEGFR-2 with IC50 values of 6 nM, 22 nM and 90 nM, respectively.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of June 22, 2024


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