345627-90-9 BMS387032 HCl AKSci SYN1080
 
 
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  SYN1080    
BMS387032 HCl
, >95%
 
BMS387032
SNS-032




IDENTITY
CAS Number:345627-90-9
MDL Number:MFCD16038304
MF:C17H24N4O2S2.HCl
MW:416.99
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>95%
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO 76mg/mL, Ethanol 1mg/mL
Application(s):CDK2 - CDK7 - CDK5 - CDK4

REVIEW

 BMS387032 is a novel cyclin-dependent kinase inhibitor, which exhibits potent and selective inhibitory activity against Cdk2, Cdk7, and Cdk9. It inhibits CDK2 with an IC50 of 48 nM and up to 20-fold selective over CDK1/CDK4. It also inhibits CDK7/9 with IC50 values of 62 nM and 4 nM. It has little effect on CDK6.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of April 15, 2024


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