501437-28-1 BI-D1870 AKSci SYN1020
 
 
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  SYN1020    
BI-D1870
, >95%
 
BID1870




IDENTITY
CAS Number:501437-28-1
MDL Number:MFCD11223662
MF:C19H23F2N5O2
MW:391.42
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>95%
Long-Term Storage:Store at room temperature
HAZARDOUS MATERIALS INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO 78mg/mL, Ethanol <1mg/mL
Application(s):S6K

REVIEW

 BI-D1870 is a small molecule, specific inhibitor of p90 RSK (ribosomal S6 kinase) isoforms RSK1, RSK2, RSK3 and RSK4, both in vitro and in vivo, with IC50s are 31 nM, 24 nM, 18 nM, 15 nM, respectively. It shows a 10- to 100-fold selectivity for RSK over MST2, GSK-3β, MARK3, CK1 and Aurora B.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of August 3, 2021


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