2-Amino-3-(4-bromobenzoyl)benzeneacetic acid sodium salt
Bromfenac sodium
IDENTITY
CAS Number:
120638-55-3
MDL Number:
MFCD26940148
MF:
C15H11BrNNaO3·1.5H2O
MW:
383.15 (356.15 anhy)
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:
98% (HPLC)
Physical Form (at 20°C):
Solid
Melting Point:
285-292°C
Long-Term Storage:
Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material
BIOLOGICAL INFO
Solubility:
H2O: =5 mg/mL
REVIEW The mechanism of its action is thought to be due to its ability to block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2. Prostaglandins have been shown in many animal models to be mediators of certain kinds of intraocular inflammation. In studies performed in animal eyes, prostaglandins have been shown to produce disruption of the blood-aqueous humor barrier, vasodilation, increased vascular permeability, leukocytosis, and increased intraocular pressure.
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