71731-58-3 Tiquizium bromide AKSci R610
 
 
Loading Please Wait...
  R610    
Tiquizium bromide, 98% (HPLC)
 
Thiaton
IDENTITY
CAS Number:71731-58-3
MDL Number:MFCD00941407
MF:C19H24NS2.Br
MW:410.44
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:295-297°C (dec)
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW
 Tiquizium bromide is a quaternary ammonium salt, an antimuscarinic agent used as a antispasdomdic pain mediating drug. The compound also demonstrates bronchodilatory effect on airway smooth muscle in vitro, and also in patients with chronic obstructive pulmonary disease (COPD).

REFERENCES
[1]Koshinaka, Eiichi; Ogawa, Nobuo; Kurata, Sakae; Yamagishi, Kagari; Kubo, Shinji; Matsubara, Issei; Kato, Hideo Studies on antispasmodics. I. Synthesis and anticholinergic activity of 1-, 2-, and 3-diarylmethylenequinolizidine quaternary ammonium salts. Chemical & Pharmaceutical Bulletin (1979), 27(6), 1454-63.
[2] Oshita, Masafumi; Ohashi, Tetsuo; Morikawa, Kouji; Kato, Hideo; Ito, Yasuo; Muramatsu, Ikunobu; Studies on the affinity and selectivity of tiquizium bromide (HSR-902), a novel spasmolytic agent, for muscarinic receptors. Japanese Journal of Pharmacology (1987), 44(2), 222-4.
[3] Oshita M, Ohashi T, Morikawa K, Kato H, Ito Y, Muramatsu I. Studies on the affinity and selectivity of tiquizium bromide (HSR-902), a novel spasmolytic agent, for muscarinic receptors. Jpn J Pharmacol. 1987 Jun;44(2):222-4.
[4] Shioya, T.; Kagaya, M.; Sano, M.; Itaba, M.; Shindo, T.; Miura, M.; Antimuscarinic effect of tiquizium bromide in vitro and in vitro. European Journal of Clinical Pharmacology (1996), 50(5), 375-380.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of September 15, 2024


Download SDS Request COA

All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
 APIs and Bioactives > AChR Antagonists


PubChem
  @PubMed