1691-99-2 N-Ethyl-N-(2-hydroxyethyl)perfluorooctylsulphonamide, tech. AKSci P903
 
 
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  P903    AKSci Bulk Reagent
N-Ethyl-N-(2-hydroxyethyl)perfluorooctylsulphonamide, tech., ~80%
 
N-EtFOSE
IDENTITY
CAS Number:1691-99-2
MDL Number:MFCD00972159
MF:C12H10F17NO3S
MW:571.25
EINECS:216-887-4
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:~80%
Physical Form (at 20°C):Solid
Melting Point:55-65°C
Boiling Point:115-120°C/1mmHg
Density:1.71
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW
 N-Ethyl-N-(2-hydroxyethyl)perfluorooctylsulphonamide or EtFOS is a synthetic fluorosurfactant used in oil- and water-repellant-coatings, N-EtFOSE is expected to enter landfills and wastewater treatment plants, where microbial transformations may take place. Potential transformation products of N-EtFOSE include perfluorooctane sulfonate, which has been shown to be toxic at high levels. Studies into microbial degradation is on going. Toxicoligcal studies have indicated that N-EtFOSE alters superoxide dismutase acivity in female rats, and the compound interacts rat liver fatty acid binding protein, resulting in rat toxicity .

REFERENCES
[1]Xie W, Wu Q, Kania-Korwel I, Tharappel JC, Telu S, Coleman MC, Glauert HP, Kannan K, Mariappan SV, Spitz DR, Weydert J, Lehmler HJ (2009). Subacute exposure to N-ethyl perfluorooctanesulfonamidoethanol results in the formation of perfluorooctanesulfonate and alters superoxide dismutase activity in female rats. Arch Toxicol. 83(10):909-24. PMID 19544052.
[2] Benskin JP, Ikonomou MG, Gobas FA, Begley TH, Woudneh MB, Cosgrove JR. Biodegradation of N-ethyl perfluorooctane sulfonamido ethanol (EtFOSE) and EtFOSE-based phosphate diester (SAmPAP diester) in marine sediments. Environ Sci Technol. 2013 Feb 5;47(3):1381-9.
[3] Nguyen VT, Reinhard M, Karina GY. Occurrence and source characterization of perfluorochemicals in an urban watershed. Chemosphere. 2011 Feb;82(9):1277-85.
[4] Luebker DJ, Hansen KJ, Bass NM, Butenhoff JL, Seacat AM. Interactions of fluorochemicals with rat liver fatty acid-binding protein. Toxicology. 2002 Jul 15;176(3):175-85.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 19, 2024


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⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


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