539-86-6 Allicin (mixture of isomers) AKSci P489
 
 
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  P489    AKSci Technical Grade
Allicin (mixture of isomers), 97%
 
S-Allyl prop-2-ene-1-sulfinothioate
IDENTITY
CAS Number:539-86-6
MDL Number:MFCD00468100
MF:C6H10OS2
MW:162.27
EINECS:208-727-7
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:97%
Physical Form (at 20°C):Liquid
Density:1.112
Refractive Index:1.561
Long-Term Storage:Store long-term at -20°C
Note:Heavy metal (Pb) <10ppm As <3ppm
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):A compound that exhibits antimicrobial, antioxidant, antiproliferative activity

REVIEW
 Allicin, an active compound of garlic, is unstable in aqueous solution and rapidly decomposes mainly to diallyl sulfide (DAS), diallyl disulfide (DADS), diallyl trisulfide (DATS), and ajoene. DATS and DADS act as H2S donors. H2S plays a cell signalling role similar to NO and CO. Exhibits antimicrobial, antioxidant, antiproliferative, chemopreventive, antihyperlipidaemic and antihypertensive effects. Inhibits telomerase activity. Induces apoptosis. Also inhibits inducible nitric oxide synthase (iNOS; NOS II) expression.

REFERENCES
[1]Ankri, S., et al. 1997. Antimicrob. Agents Chemother. 41: 2286-2288. PMID: 9333064
[2] Dirsch, V.M., et al. 1998. Atherosclerosis 139: 333-339. PMID: 9712340
[3] Ankri, S. and Mirelman, D. 1999. Microbes Infect. 1: 125-129. PMID: 10594976
[4] Hirsch, K., et al. 2000. Nutr. Cancer 38: 245-254. PMID: 11525603

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 23, 2024

AKSci Technical Grade compounds are suitable for commercial and industrial applications, and in areas where official standards may not yet exist.


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⚠️
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CATEGORIES
 APIs and Bioactives > Antibacterials


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