2586-96-1 Liensinine AKSci O903
 
 
Loading Please Wait...
  O903    AKSci Reference Standard
Liensinine, 98%
 



IDENTITY
CAS Number:2586-96-1
MDL Number:MFCD03427702
MF:C37H42N2O6
MW:610.74
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98%
Physical Form (at 20°C):Solid
Melting Point:95-99°C
Density:1.2
Refractive Index:1.61
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW
 Liensinine (neferine), a isoquinoline alkaloid, extracted from the green seed embryo of Nelumbo nucifera Gaertn has been shown to have anti-arrhythmic action, its mechanism may be related to blockade of Ca2+ and Na+ influx. Liensinene has also shown a potential neuroprotective effect in rats, in regard to focal cerebral ischemia, whereby liensinen inhibited the expression of C-Fos, which significantly increased after 24-h ischemia without the treatment of the compound.

REFERENCES
[1]Chao, Yuan Chih; Chou, Yun-Li; Yang, Pao-Chin; Chao, Chen-Ku; Alkaloids of embryo Nelumbo nucifera. I. Isolation and characterization of liensinine , Scientia Sinica (English Edition) (1962), 11, 215-19.
[2] Hsieh, Yu-Yuan; Pan, Pei-Chuan; Chen, Wen-Chi; Kao, Yee-Sheng; Alkaloids of Nelumbo nucifera. IV. Total synthesis of liensinine Scientia Sinica (English Edition) (1964), 12(12), 2020-5.
[3] Wang, J. L.; Nong, Y.; Jing, M. X. Effects of liensinine on hemodynamics in rats and the physiologic properties of isolated rabbit atria Yaoxue Xuebao (1992), 27(12), 881-5.
[4] Wang, J. L.; Nong, Y.; Xia, G. J.; Yao, W. X.; Jiang, M. X. Effects of liensinine on slow action potential in myocardium and slow inward current in canine cardiac Purkinje fibers. Yaoxue Xuebao (1993), 28(11), 812-16.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 19, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


Download SDS Request COA

All products are stocked and shipped from San Francisco Bay Area, California, USA.

⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
 APIs and Bioactives > Alkaloids


PubChem
  @PubMed