51-60-5 Neostigmine methyl sulfate AKSci O811
 
 
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  O811    AKSci Reference Standard
Neostigmine methyl sulfate
, 98%
 
3-(N,N-Dimethylcarbamoyloxy)-N,N,N,-trimethylanilinium methyl sulfate
(3-Hydroxyphenyl)trimethylammonium Methyl Sulfate Dimethylcarbamate




IDENTITY
CAS Number:51-60-5
MDL Number:MFCD00011796
MF:C13H22N2O6S
MW:334.39
SPECIFICATIONS & PROPERTIES
Purity:98%
Spectra:NMR, LCMS
Physical Form:White crystalline powder
Melting Point:146-148°C
Long-Term Storage:Store long-term at 2-8°C
UN #:UN2811
Hazard Class:6.1
Packing Group:II

BIOLOGICAL INFO
Application(s):Cholinesterase inhibitor

REVIEW

 Neostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor. The drug inhibits acetylcholinesterase which is responsible for the degredation of acetylcholine. So, with acetylcholinesterase inhibited, more acetylcholine is present By interfering with the breakdown of acetylcholine, neostigmine indirectly stimulates both nicotinic and muscarinic receptors which are involved in muscle contraction.. It does not cross the blood-brain barrier.

GHS

Pictograms

Signal Word
Danger

Hazard Statements
H300; H315; H319; H334; H335

Precautionary Statements
P261; P264; P270; P271; P280; P285; P301+P310; P302+P352; P304+P340; P305+P351+P338; P321; P330; P332+P313; P337+P313; P342+P311; P362; P403+P233; P405; P501


Current as of March 20, 2019

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > AChR Agonists


PubChem