37248-47-8 Validamycin A AKSci O743
 
 
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  O743    
Validamycin A
, 95% (HPLC)
 
2-[2,3-Dihydroxy-6-(hydroxymethyl)-4-[[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]cyclohexyl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol




IDENTITY
CAS Number:37248-47-8
MDL Number:MFCD09028089
MF:C20H35NO13
MW:497.49
SPECIFICATIONS & PROPERTIES
Purity:95% (HPLC)
Spectra:NMR, LCMS, HPLC
Physical Form:White to light yellow powder
Melting Point:188-194°C
Optical Rotation:+44° - +50° (c=1, H2O)
Long-Term Storage:Store long-term at 2-8°C

REVIEW

 Validamycin A is an antibiotic and fungicide produced by Streptomyces hygroscopicus. It is used as an inhibitor of trehalase. It is used for the control of sheath blight of rice and damping-off of cucumbers.

REFERENCES
[1]Horii, Satoshi; Kameda, Yukihiko Structure of the antibiotic validamycin A Journal of the Chemical Society, Chemical Communications (1972), (12), 747-8.
[2] Manufacture of validoxylamine A derivatives Jpn. Kokai Tokkyo Koho (1981), JP 56012399 A 19810206.
[3] Ogawa, Seiichiro; Ogawa, Takao; Nose, Taisuke; Toyokuni, Tatsushi; Iwasawa, Yoshikazu; Suami, Tetsuo A formal total synthesis of validamycin A Chemistry Letters (1983), (6), 921-2.
[4] Mahmud, Taifo; Lee, Sungsook; Floss, Heinz G. The biosynthesis of acarbose and validamycin Chemical Record (2001), 1(4), 300-310.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of April 10, 2020


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For research use only. Not for diagnostic or therapeutic use.
Not for human use.


CATEGORIES

 APIs and Bioactives > Fungicides


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