REVIEW Sulbutiamine (isobutyryl thiamine disulfide) is a lipophilic derivative of thiamine used for the treatment of asthenia and other related pathological conditions. Sulbutiamine is available over-the-counter in several countries as a component of nutritional supplements.
van Reeth, O., et al.: Drugs Today, 35, 187 (1999)
Micheau, J., et al.: Pharmacol. Biochem. Behav., 23, 195 (1985)
Bettendorff, L., et al.: Biochem. Pharmacol., 40, 2557 (1990)