10605-09-1 L-Ascorbic acid 6-stearate AKSci O450
 
 
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  O450    
L-Ascorbic acid 6-stearate
 



IDENTITY
CAS Number:10605-09-1
MDL Number:MFCD00059739
MF:C24H42O7
MW:442.59
EINECS:234-231-5
SPECIFICATIONS & PROPERTIES
Physical Form:Crystalline Powder
Melting Point:117°C
Optical Rotation:21° (C=1,EtOH)
Density:1.125
Long-Term Storage:Store at room temperature
HAZARDOUS MATERIALS INFORMATION
Not hazardous material

REVIEW

 L-Ascorbic acid 6-stearate is the stearate ester of L-ascorbic acid and as well as source of vitamin C, it is used as an antioxidant food additive in margarine (E number E305). The USDA limits its use to 0.02% individually or in conjunction with other antioxidants. L-Ascorbic acid 6-stearate has also been used in the preparation of nanoparticles for drug delivery and the food industry.

REFERENCES
[1]Frungillo L, Martins D, Teixeira S, Anazetti MC, Melo Pda S, Durán N. Targeted antitumoral dehydrocrotonin nanoparticles with L-ascorbic acid 6-stearate. J Pharm Sci. (2009) Dec;98(12): 4796-807.
[2] Sharma, R.; Pathak, Y. Enzymatic synthesis: acyl ascorbate and its industrial use as a food additive Edited by Laudon, Matthew; Romanowicz, Bart. Nanotech Conference & Expo 2010: An Interdisciplinary Integrative Forum on Nanotechnology, Biotechnology and Microtechnology, Anaheim, CA, United States, June 21-24, 2010. (2010) 1: 79-82.
[3] Kulesza, Janusz; Gora, Jozef; Krygier, Janusz. Synthesis of L-ascorbinyl stearate and benzoate, Zeszyty Naukowe - Politechnika Lodzka, Seria: Chemia Spozywcza. (1967) No. 12: 29-32.
[4] Enomoto, Kanehiko; Miyamori, Takao; Sakimae, Akihiro; Numazawa, Ryozo Manufacture of ascorbic acid esters or erythorbic acid esters with esterase Jpn. Kokai Tokkyo Koho (1991), JP 03259089 A 19911119

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of June 23, 2021


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CATEGORIES

 APIs and Bioactives > Vitamins


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