REVIEW Temocapril HCl is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension. It is a prodrug with a thiazepine ring, with temocaprilat being its active form. It is currently only approved for use in Japan.
REFERENCES
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Jia Nan; Okamoto Hiroshi; Shimizu Toshihiro; Chiba Satoru; Matsui Yutaka; Sugawara Takeshi; Akino Masatoshi; Kitabatake Akira; A newly developed angiotensin II type 1 receptor antagonist, CS866, promotes regression of cardiac hypertrophy by reducing integrin beta1 expression Hypertension research: official journal of the Japanese Society of Hypertension (2003), 26(9), 737-42.
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Yasunari K, Maeda K, Nakamura M, Watanabe T, Yoshikawa J, Asada A. Pharmacological and clinical studies with temocapril, an angiotensin converting enzyme inhibitor that is excreted in the bile. Cardiovasc Drug Rev. 2004 Fall;22(3):189-98.
Shionoiri, Hiroshi; Ochiai, Hisao; Hiroto, Seiji; ACE inhibitor, temocapril hydrochloride, excreted from bile and kidney. Cardiac Practice (1995), 6(4), 487-94.
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