4779-94-6 Norfenefrine HCl AKSci O385
 
 
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  O385    
Norfenefrine HCl
, 98% (HPLC)
 
3-(2-amino-1-hydroxyethyl)phenol HCl, DL-Norphenylephrine Hydrochloride




IDENTITY
CAS Number:4779-94-6
MDL Number:MFCD00012879
MF:C8H11NO2.HCl
MW:189.64
EINECS:225-323-6
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Spectra:NMR, LCMS, FT-IR, HPLC
Physical Form:White powder
Melting Point:162-164°C
Long-Term Storage:Store at room temperature

BIOLOGICAL INFO
Application(s):Adrenergic agent
Form:HCl salt

REVIEW

 Norfenefrine (brand names Coritat, Energona, Hypolind, and Novadral), also known as m-octopamine (or 3-octopamine) and 3, alpha-dihydroxyphenethylamine, is an adrenergic agent used as a sympathomimetic drug which is marketed in Europe, Japan, and Mexico, where it is used in the treatment of hypertension. Along with its structural isomer p-octopamine and the tyramines, norfenefrine is a naturally occurring, endogenous trace amine and plays a role as a minor neurotransmitter in the brain.

REFERENCES
[1]Gebler, Herbert Novadral [drug report]. der Praktischen Pharmazie (1979), 8(7), 218-19.
[2] Danielson TJ, Boulton AA, Robertson HA. m-Octopamine, p-octopamine and phenylethanolamine in rat brain: a sensitive, specific assay and the effects of some drugs. J Neurochem. 1977 Dec;29(6):1131-5.
[3] Fregly, Melvin J.; Kelleher, D. L.; Williams, C. M. Adrenergic activity of ortho-, meta-, and para-octopamine. Pharmacology (1979), 18(4), 180-7.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of July 2, 2020


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CATEGORIES

 APIs and Bioactives > Adrenergic Agonists


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