REVIEW Neocuproine is a phenanthroline based metal ion chelating agent. With copper (I) ions,it forms a complex with a deep red color. This complex has been shown to possess antitumor activity which can be related to copper toxicity.
REFERENCES
[1]
Mohindru A, Fisher JM, Rabinovitz M. 2,9-Dimethyl-1,10-phenanthroline (neocuproine): a potent, copper-dependent cytotoxin with anti-tumor activity. Biochem Pharmacol. 1983 Dec 1;32(23):3627-32.
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